Here are some of the topics in genetics that interest me, with some related papers that I’ve been involved in:
Population genomics. With plentiful whole-genome sequence, one can describe the genetic variation of populations in ever finer detail. I am interested in genetic variation, signatures of selection and recombination rate variation in domestic and feral animals.
Related papers: Johnsson et al. 2016, Gering et al. 2015, Johnsson et al. 2018, Johnsson, Whalen et al. 2021
Genetic mapping of complex traits. I am interested in the genetic basis of complex traits that matter to farm animals, such as body size and bone quality. Mapping the genetic basis of molecular traits such as transcript levels (”eQTL mapping”) can help with identifying causative genes for quantitative traits, and also give us large sets of genetic associations to analyse.
Related papers: Johnsson et al. 2018, Johnsson et a. 2016, Johnsson et al. 2015
Deleterious variation. Deleterious variants are the most tractable functional variants, and can be detected either by genotype-first or sequence-first methods. They raise all kinds of interesting management questions for breeding programs.
Related papers: Johnsson et al. 2019, Jenko et al. 2019
Domestication. Domestic animals differ from their wild relatives in many ways, including behavioural differences towards humans and other complex traits. I have been involved in genetic mapping of complex traits in chicken domestication.
Related papers: Johnsson et al. 2021, Johnsson et al. 2016, Henriksen et al. 2016, Fallahsharoudi et al. 2017
Blog posts about my research
Here are some blog posts about my work:
Paper: ”Genetic variation in recombination rate in the pig”
Preprint: Genetics of tibia bone properties of crossbred commercial laying hens in different housing systems”
Paper: ”Removal of alleles by genome editing (RAGE) against deleterious load”
Paper: ”Sequence variation, evolutionary constraint, and selection at the CD163 gene in pigs”
Paper: ”Feralisation targets dfferent genomic loci to domestication in the chicken”
Paper: ”Mixed ancestry and admixture in Kauai’s feral chickens: invasion of domestic genes into ancient Red Junglefowl reservoirs”
Paper: ”Heritable genome-wide variation of gene expression and promoter methylation between wild and domesticated chickens”
If you’re interested, see my publication list at Google Scholar.